Lexapro

Lexapro medicine is prescribed for major depression - a persistently low mood that interferes with daily functioning. To be considered major, depression must occur nearly every day for at least two weeks, and must include at least five of the following symptoms: low mood, loss of interest in usual activities, significant change in weight or appetite, change in sleep patterns, agitation or lethargy, fatigue, feelings of guilt or worthlessness, slowed thinking or lack of concentration, and thoughts of suicide.

Lexapro works by boosting levels of serotonin, one of the chief chemical messengers in the brain. The drug is a close chemical cousin of the antidepressant medication citalopram. Other antidepressants that work by raising serotonin levels include fluoxetine, paroxetine, and sertraline.

Lexapro is also prescribed for generalized anxiety disorder, a condition marked by excessive worry and anxiety that is hard to control and interferes with daily life. To be diagnosed with this disorder, your symptoms must have lasted at least 6 months and you must have at least three of the following: restlessness, fatigue, poor concentration, irritability, muscle tension, and sleep disturbances.

Things to remember when taking Lexapro

Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin and NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with escitalopram may cause you to bruise or bleed easily.

Avoid drinking alcohol, which can increase some of the side effects of Lexapro. Lexapro can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety). They can add to sleepiness caused by Lexapro.

Do not take Lexapro for 2 weeks before or after taking any drug classified as an MAO inhibitor. Drugs in this category include the antidepressants phenelzine and tranylcypromine. Combining these drugs with Lexapro can cause serious and even fatal reactions marked by such symptoms as fever, rigidity, twitching, and agitation leading to delirium and coma.

Side effects of Lexapro

Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • very stiff (rigid) muscles, high fever, sweating, fast or uneven heartbeats, tremors, overactive reflexes;

  • nausea, vomiting, diarrhea, loss of appetite, feeling unsteady, loss of coordination; or

  • headache, trouble concentrating, memory problems, weakness, confusion, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

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